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pentobarbital will decrease the level or result of prednisone by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.pentobarbital will decrease the extent or effect of siponimod by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Steer clear of or Use Alternate Drug. Coadministration of siponimod which has a dru